The Truth About Horse Joint Supplements (Part 2)

Grandflex-Frequently copied and never replicated

Since Grand Flex's original glucosamine joint support formula was developed in 1994, many companies have tried to copy Grand Flex's unique formula. In many initial reviews following Michael Plumb's Equine Journal, one of the most respected horse consumer publications in the United States, Grand Flex found glucosamine levels and the number of key cofactors in 1997. It also includes Grandflex, vitamin C and bioflavonoids, niacinamide, and all the minerals and amino acids essential for joint and connective tissue health. After the new glucosamine products are on the market, many of these products have Grand Flex formulas & tokens in our opinion, plans to make absorption and health benefits easier Rather than being added as a "window dressing".

Since the first positive review of Grandflex in 1997-2008, Michael Plumhorse Journal has given Grandflex the highest rating of the best recommended joint support prescription with long-term joint health benefits. Keep giving.

Glucosamine HSL VS. Glucosamine Sulfate: Grand Meadows Perspective

There is an endless discussion about the difference between glucosamine HCL and glucosamine sulfate. Glucosamine sulfate is used in early clinical reviews and is a combination of sulfur salts -40% sulfur and 60% glucosamine. Glucosamine HCL is a new purified version containing 98% pure active glucosamine. Sulfur is an important part of a synergistic approach to include sulfur in collaborative support and more bioavailable forms.
Methionine and MSM are much more effective and efficient elemental sulfur sources.

Chondroitin sulfate

Glucosamine is clearly the main ingredient in the market when it comes to joint supplements, but chondroitin sulfate has long been thought of as the other half of the formula required for a joint product to be effective. Chondroitin is a component of cartilage that provides structure, retains water and nutrients, and allows other molecules to move through the cartilage. This is an important characteristic because there is no blood supply to the cartilage. There is no question about the function of this ingredient when it is naturally produced in the body. Many glucosamine products advertise the inclusion of chondroitin sulfate from bovine compounds as a necessary and beneficial additive to glucosamine. Such competition is misleading. In the past few years, a number of important scientific studies have been conducted that ultimately show insufficient absorption of the orally administered supplement form of chondroitin. Chondroitin sulfate absorption results are very low [from 250 times the size of the glucosamine molecule] due to the very large molecular structure. There have been many major studies supporting this theory. The New England Medical Journal concluded that oral absorption of chondroitin is less than 12%. The natural medicine encyclopedia states that "absorption of intact chondroitin sulfate is estimated to be in the range of 0 to 13 percent." Dr. Ian Wright, UK's leading veterinary orthopedist, wrote in "Horse and Hounds": “A supplement containing chondroitin sulfate can be given to horses at the recommended dose. Not absorbed.” Surprisingly, most manufacturers continue to add it to their products.

Chondroitin sulfate: Grand Meadows perspective

Due to the considerable level of research that indicates poor absorption, we chose not to use chondroitin sulfate as a single ingredient in our products due to its large molecular size. It is absorbed efficiently. The health benefits of chondroitin sulfate cannot be effectively realized when administered as an oral ingredient. However, it uses depolymerized chondroitin sulfate, which is indispensable as a raw material for BioCell Collagen II ™. This component, along with this triple patented component of hyaluronic acid and type II collagen, has been subjected to a manufacturing process that results in a highly bioavailable component matrix, all reduced to 1/90 of its original size.